\(x^4-2x^2-100x-624=0\\ \Rightarrow\left(x^4+4x^3\right)-\left(4x^3+16x^2\right)+\left(14x^2+56x\right)-\left(156x-624\right)=0\\ \Rightarrow x^3\left(x+4\right)-4x^2\left(x+4\right)+14x\left(x+4\right)-156\left(x+4\right)=0\\ \Rightarrow\left(x^3-4x^2+14x-156\right)\left(x+4\right)=0\\ \Rightarrow\left[\left(x^3-6x^2\right)+\left(2x^2-12x\right)+\left(26x-156\right)\right]\left(x+4\right)=0\\ \Rightarrow\left[x^2\left(x-6\right)+2x\left(x-6\right)+26\left(x-6\right)\right]\left(x+4\right)=0\)
\(\Rightarrow\left(x^2+2x+26\right)\left(x-6\right)\left(x+4\right)=0\\ \Rightarrow\left[{}\begin{matrix}\left(x+1\right)^2+25=0\left(vô.lí\right)\\x=6\\x=-4\end{matrix}\right.\)
Vậy pt có tập nghiệm \(S=\left\{-4;6\right\}\)